US 12,447,354 B2 · Illumination devices for inducing biological effects

Abstract

Illumination devices for impinging light on tissue, for example within a body cavity of a patient, to induce various biological effects are disclosed. Biological effects may include at least one of inactivating and/or inhibiting growth of one or more pathogens, upregulating a local immune response, increasing endogenous stores of nitric oxide, releasing nitric oxide from endogenous stores, and inducing an anti-inflammatory effect. Wavelengths of light are selected based on intended biological effects for one or more of targeted tissue types and targeted pathogens. Light treatments may provide multiple pathogenic biological effects, either with light of a single wavelength or with light having multiple wavelengths. Devices for light treatments are disclosed that provide light doses for inducing biological effects on various targeted pathogens and tissues with increased efficacy and reduced cytotoxicity. Illumination devices may be configured to communicate with networks and/or servers to provide control and/or management of phototherapy treatments.

Claims29

Dependent claims

An illumination device comprising:

at least one light source;
at least one camera;
a communication module;
and
driver circuitry associated with the communication module, the at least one light source, and the at least one camera, the driver circuitry configured to:
control the at least one camera to capture one or more images of a target area of the mammalian tissue and relay the one or more images to a server via the communication module;
receive a treatment protocol comprising at least one parameter from the server via the communication module, the treatment protocol comprising one of a pre-exposure prophylaxis treatment, a post-exposure prophylaxis treatment based on identification of at least one pathogen in a cell-free environment with respect to a surface of the mammalian tissue, and a post-infection treatment based on identification of at least one pathogen in a cell-associated environment with respect to the mammalian tissue;
and
control the at least one light source to irradiate the light on the target area of the mammalian tissue to induce at least one biological effect.

6 more elements

Dependencies are inferred from the claim text.

Illumination devices for inducing biological effects

Life of this patent

Illumination devices for inducing biological effects

Life of this patent

Abstract

Claims29