US 12,447,282 B2Granted

Auto-injector

AssigneeSanofi-Aventis Deutschland GmbH

InventorsSimon Francis Brereton, Thomas Kemp, Rosie Burnell, Matthew Ekman

Life of this patent

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Abstract

An auto-injector for administering a dose of a liquid medicament includes an elongate tubular case and a carrier subassembly including a tubular carrier slidably arranged inside the case. The carrier is adapted to contain a syringe with a hollow injection needle, a drive spring, and a plunger for forwarding load of the drive spring to a stopper of the syringe, wherein the syringe is lockable for joint axial translation with the carrier, wherein the drive spring acts between the carrier and the plunger, wherein the plunger, in an initial state, is locked to the carrier by a ramped engagement to the carrier and by being prevented from rotating out of this ramped engagement, depending on a relative longitudinal position of the carrier in the case, and wherein the plunger is arranged to be released for rotating out of the ramped engagement.

Claims20

Dependent claims

An autoinjector comprising:

a carrier;
a plunger releasably engaged to the carrier to form a ramped interface between the carrier and the plunger, wherein the plunger, when released from the carrier, is arranged to be driven in a proximal direction relative to the carrier for a delivery operation;
a drive spring biasing the plunger in the proximal direction relative to the carrier to drive the delivery operation, wherein the autoinjector is configured such that the plunger rotates relative to the carrier under load of the drive spring due to the ramped interface when the plunger engages the carrier;
and
a chassis that is movable relative to the carrier and the plunger between a first position and a second position, wherein, when the chassis is in the first position, rotation of the plunger relative to the carrier is prevented by a longitudinal rib abutting the plunger, and wherein the autoinjector is configured such that a relative axial movement between the plunger and the longitudinal rib is required to release the plunger from the carrier for the delivery operation.

2 more elements

Dependencies are inferred from the claim text.

Facts

Application: 17/935,237Filed 26 Sep 2022 · continuation
Priority: EP 1115504118 Feb 2011
Published: US 2023/0082328 A116 Mar 2023
Granted: 21 Oct 2025
Term ends: Not estimatedThe source records don’t support an estimate.

Classification23 codes

A61M 5/3158
The piston rod being moved by the axial movement of a component directly in contact with it: the component being manually operated or triggered by…
A61M 5/2033
Automatic syringes, e.g. with automatically actuated piston rod, with automatic needle injection, filling automatically: spring-loaded one-shot…
A61M 5/31501
Pistons; Piston-rods; Guiding, blocking or restricting the movement of the rod or piston; Appliances on the rod for facilitating dosing ; Dosing…:…
A61M 5/31511
Pistons; Piston-rods; Guiding, blocking or restricting the movement of the rod or piston; Appliances on the rod for facilitating dosing ; Dosing…:…

Family

PCT/EP2012/052648Parent of this continuation · filed 16 Feb 2012
Application15/452,346Parent of this division · filed 7 Mar 2017
US 9,623,181 B2Parent of this continuation · filed 18 Apr 2017
Application16/667,008Parent of this continuation · filed 29 Oct 2019
US 10,471,210 B2Parent of this division · filed 12 Nov 2019
US 2023/0082328 A1Pre-grant publication · published 16 Mar 2023
US 11,484,655 B2Parent of this continuation
Application16/667,008Parent of this division
Application13/985,021Parent of this continuation
Application15/452,346Parent of this continuation
US 2013/0324925 A1Published application
US 2017/0246397 A1Published application
US 2020/0078524 A1Published application
US 12,447,282 B2This patent

From the US filing history. Foreign family members aren’t listed.