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US 12,447,243 B2Granted
4% trisodium citrate solution for use as a catheter lock solution
AssigneeBecton, Dickinson and Company
InventorsRoza Mahmoodian, Suzanne Ferreri
Life of this patent
Estimating the term…
Abstract
Provided herein are catheter lock solutions having anticoagulation and antimicrobial properties, the catheter lock solutions including citrate salts. The citrate salt can be trisodium citrate, and the catheter lock solution can further include a diluted acid for adjusting the pH of the catheter lock solution.
Claims10
A catheter lock solution comprising:
- about 3 4% w/v, based on a total volume of the lock solution, of trisodium citrate;
- water for injection;
- and, about 0.7% v/v of 10% HCl, based on the total volume of the lock solution,
- wherein a pH of the catheter lock solution is between about 6.4 and about 7.5, and wherein the catheter lock solution includes no additional anticoagulant or antimicrobial additives.
1 more element
A catheter lock solution comprising:
- about 3.8% w/v to about 4.2% w/v, based on a total volume of the lock solution, of trisodium citrate;
- water for injection;
- and
- an amount of HCl sufficient to maintain a pH of the catheter lock solution between about 6.4 and about 7.5,
- wherein the catheter lock solution includes no additional anticoagulant or antimicrobial additives.
2 more elements
A catheter lock solution consisting of:
- about 3.8% w/v to about 4.2% w/v of trisodium citrate;
- water-for-injection (WFI);
- and
- an amount of HCl sufficient to maintain a pH of the catheter lock solution between about 6.4 and about 7.5.
1 more element
Dependencies are inferred from the claim text.