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US 12,447,228 B2Granted
Polymer particles
AssigneeTerumo Kabushiki Kaisha
InventorsGregory M. Cruise, Xinping Wu, Gloria Hincapie, Yue Wu
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Abstract
Described are polymers and methods of forming and using same.
Claims20
A method of treatment comprising:
- administering a solution including a plurality of particles to a treatment site;
- wherein the plurality of particles include a reaction product of at least one monomer, at least one crosslinker, and at least one polymerizable pharmaceutical agent;
- wherein the at least one polymerizable pharmaceutical agent is chemically bonded to the particle with a hydrolytically degradable linkage;
- and
- wherein the at least one polymerizable pharmaceutical agent has a structure which is a polymerizable derivative of 7-ethyl-10-hydroxy-camptothecin.
2 more elements
Dependencies are inferred from the claim text.