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US 12,447,200 B2Granted
Compositions and methods for protecting against airborne pathogens and irritants
AssigneeApplied Biological Laboratories, Inc.
InventorNazlie Latefi
Life of this patent
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Abstract
The present disclosure features methods and compositions for enhancing the ability of the respiratory membranes to filter airborne pathogens and protect a subject from respiratory infections that result from inhalation of such pathogens. In particular, the disclosure provides antimicrobial compositions that prevent and treat respiratory infections caused by bacteria, fungi, and viruses.
Claims15
A pharmaceutical composition for prophylaxis or treatment of respiratory infection comprising:
- (i) soluble ICAM-1;
- (ii) sialic acid;
- (iii) lysozyme;
- and
- (iv) lactoferrin;
- and
- a pharmaceutically acceptable carrier
- wherein components (i)-(iv) are present in said composition in individual form,
- wherein said pharmaceutically acceptable carrier is adapted to provide a residence time of said pharmaceutical composition on the nasal and/or oral mucosa of at least 5 minutes,
- the weight ratio of said component (i) to said components (iii) and (iv) active agent is about 1:100 to about 1:200 and
- the weight ratio of said component (iii) to component (iv) is about 1:4 to about 1:20.
8 more elements
Dependencies are inferred from the claim text.