Compositions and methods for the antiseptic treatment of biofilms on mammalian tissue
AssigneeAvadim Holdings, Inc.
InventorStephen Thomas Woody
Life of this patent
Estimating the term…
Abstract
Compositions and methods for providing the hybrid benefit of treating biofilms on the surface of mammalian tissue, especially biofilms that occur in association with chronic wounds and burns, and simultaneously providing an antiseptic cleansing and maintenance of the stratum corneum of the tissue and other tissue surfaces, and an opportunity for the tissue to improve by engaging its own natural barrier and immunological defense properties. The compositions and methods prevent the re-establishment of biofilms by facilitating the reduction or eradication of the pathogen producing the biofilm before the biofilm can be established.
Claims6
A composition for treating the surface of inflamed chronically infected mammalian tissue, consisting of:
- at least one ingredient selected from each of the following categories:
- an amphoteric surfactant category (a) ingredient having a wt % from about 2.0 to about 8.0 wt. %, a skin compatible anti-inflammatory category (b) ingredient having a wt % from about 6.0 to about 12.0 wt. %, and a skin compatible anti-foaming category (c) ingredient having a wt % from about 0.19 to about 0.27 wt. %;
- at least one ingredient selected from each of the following categories:
- a cell growth promoting category (d) ingredient having a wt % from about 4.0 to about 10.0 wt. %, an immune system enhancing category (e) ingredient having a weight percentage from about 2.0 to about 5.0 wt. %, a fast acting skin compatible antimicrobial category (f) ingredient having a weight percentage from about 2.0 to about 10.0 wt. %, an absorption facilitation category (g) ingredient having a weight percentage from about 0.5 to about 5.0 wt. %, a humectant and emollient category (h) ingredient having a weight percentage from about 2.0 to about 11.0 wt. %, a free radical scavenging category (i) ingredient having a weight percentage from about 4.0 to about 8.0 wt. %, and a healing promoting category (j) ingredient having a weight percentage from about 2.0 to about 4.0 wt. %;
- a biocompatible preservative category (k) ingredient of potassium sorbate having a weight percentage from about 0.01 to about 0.10 wt. %;
- and a plant based extract category (l) ingredient of olibanum (frankensense) having a weight percentage from about 0.009 wt. % to about 5.0 wt. %;
- with the balance of the composition being approximately 70 to 90 wt. % water;
- wherein the composition has an acidic pH of from 4.0 to 5.0, is gamma irradiated at 4 kGY to 35 kGY to a sterility assurance level of 10−2 to 10−6, and provides the hybrid benefits of:
- (1) treating microbials, (2) treating biofilms, (3) maintaining, nourishing and moisturizing, (4) maintaining the natural pH;
- (5) maintaining and promoting immunocompetency, and (6) protecting and preserving barrier function of the tissue's stratum corneum.
Dependencies are inferred from the claim text.