Systems and methods for pre-filled multi-liquid medical delivery devices

A pre-filled medical delivery system comprising:

• a blow-fill-seal (BFS) component comprising:
• a compressible first chamber having a first dose of a first liquid agent therein;
• a first sealed port in fluid communication with the first chamber;
• a compressible second chamber connected to the first chamber, the second chamber having a second dose of a second liquid agent therein;
• and
• a second sealed port in fluid communication with the second chamber;
• and
• a connection assembly constructed to be coupled to the BFS component so as to breach seals of the first and second sealed ports and to provide fluid communication between the first and second ports, the connection assembly including:
• a first coupling port defining a first port wall and having a first piercing member extending within a first interior of the first port wall;
• a second coupling port defining a second port wall and having a second piercing member extending within a second interior of the second port wall;
• and
• a bridge conduit or mixing chamber in fluid communication with the first coupling port and the second coupling port;
• and
• at least one administration conduit having an outlet at an end thereof spaced from the bridge conduit or the mixing chamber, the at least one administration conduit being in fluid communication with the bridge conduit or the mixing chamber;
• wherein when the connection assembly is coupled to the BFS component:
• the first and second coupling ports respectively receive at least portions of the first and second chambers such that the first and second port walls engage the portions of the first and second chambers in coupled relation therewith to couple the BFS component relative to the connection assembly;
• the first and second piercing members respectively pierce the first and second sealed ports, and
• the bridge conduit or the mixing chamber fluidly connects one of the first coupling port and the first piercing member with one of the second coupling port and the second piercing member;
• and
• wherein compression of the first chamber and the second chamber causes respective egress of the first and second fluid agents from the first and second chambers into the bridge conduit or the mixing chamber such that a combination of the first liquid agent and the second liquid agent is dispensed through the administration conduit.