Resin composition and flow cells incorporating the same
AssigneesIllumina, Inc., Illumina Cambridge Limited
InventorsTimothy J. Merkel, Wayne N. George, Andrew A. Brown, Audrey Zak, Gianluca Andrea Artioli, Julia Morrison, Nikolai Romanov, Lorenzo Berti, Graham Boud
Life of this patent
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Abstract
An example of a resin composition includes a free radical curable resin matrix including an acrylate and a siloxane, and a free radical photoinitiator. When cured, the resin composition has low or no autofluorescence when exposed to blue excitation wavelengths ranging from about 380 nm to about 480 nm or green excitation wavelengths ranging from about 510 nm to about 560 nm.
Claims5
A resin composition, consisting of:
- a free radical curable resin matrix including an acrylate and a siloxane;
- a free radical photoinitiator selected from the group consisting of 2,2-dimethoxy-2-phenylacetophenone, a blend of diphenyl(2,4,6-trimethylbenzoyl) phosphine oxide and 2-hydroxy-2-methylpropiophenone, phenylbis(2,4,6-trimethylbenzoyl) phosphine oxide, ethyl(2,4,6-trimethylbenzoyl)phenylphosphinate, and combinations thereof;
- and
- a solvent;
- wherein, when cured, the resin composition has low or no autofluorescence when exposed to blue excitation wavelengths ranging from about 380 nm to about 480 nm or green excitation wavelengths ranging from about 510 nm to about 560 nm, and
- wherein the free radical curable resin matrix is an acryloxypropyl methylsiloxane homopolymer having a structure:
- wherein m is 30 to 200.
A resin composition, consisting of:
- a free radical curable resin matrix including an acrylate and a siloxane;
- a free radical photoinitiator selected from the group consisting of 2,2-dimethoxy-2-phenylacetophenone, a blend of diphenyl(2,4,6-trimethylbenzoyl) phosphine oxide and 2-hydroxy-2-methylpropiophenone, phenylbis(2,4,6-trimethylbenzoyl) phosphine oxide, ethyl(2,4,6-trimethylbenzoyl)phenylphosphinate, and combinations thereof;
- a dark quencher selected from the group consisting of an azo dye, 4-dimethylaminobenzene-4′-carboxylic acid, dabcyl azide, dabsyl azide, disperse red 19, a black dye-based quencher, and combinations thereof;
- and
- a solvent, and
- wherein the free radical curable resin matrix is an acryloxypropyl methylsiloxane homopolymer having a structure:
- wherein m is 30 to 200.
A resin composition, consisting of:
- a free radical curable resin matrix including an acrylate and a siloxane, and being selected from the group consisting of 1,3-bis(3-methacryloxypropyl)tetramethyldisiloxane, methacryloxypropyl-terminated polydimethylsiloxane, tetramethyl tetrakis [3-acryloxypropyl]cyclotetrasiloxane, acryloxypropyl methylsiloxane homopolymer, and combinations thereof;
- a free radical photoinitiator selected from the group consisting of 2,2-dimethoxy-2-phenylacetophenone, a blend of diphenyl(2,4,6-trimethylbenzoyl) phosphine oxide and 2-hydroxy-2-methylpropiophenone, phenylbis(2,4,6-trimethylbenzoyl) phosphine oxide, ethyl(2,4,6-trimethylbenzoyl)phenylphosphinate, and combinations thereof;
- and
- a solvent;
- wherein, when cured, the resin composition has low or no autofluorescence when exposed to blue excitation wavelengths ranging from about 380 nm to about 480 nm or green excitation wavelengths ranging from about 510 nm to about 560 nm;
- and
- wherein the solvent is selected from the group consisting of propylene glycol monomethyl ether acetate, toluene, dimethyl sulfoxide, and tetrahydrofuran.
Dependencies are inferred from the claim text.