Venom-based peptide and application thereof
AssigneeUniversity of Macau
InventorsHang Fai Kwok, Rui Ma, Guokai Chen
Life of this patent
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Abstract
A venom-based peptide and an application thereof, which relate to the technical field of biomolecules. The amino acid sequence of the peptide is represented by formula 1: X1-X2-X3-X4-X5-X6-X7-X8-X9-X10-X11-X12-X13-X14-X15-X16-X17-X18; X1, X5, X6, X9 and X11 are each selected from any one among A, V, L, I, M, F, W and P; X2, X3, X10, X15, X17 and X18 are each selected from any one among G, C, S, T, Y, N and Q; X7 is selected from D or E; X4, X8 and X16 are each selected from any one among K, R and H; and X12, X13 and X14 are each selected from any one among K, R, H, D and E. The peptide has the function of promoting self-renewal of human embryonic stem cells.
Claims13
A venom-based peptide
- having an amino acid sequence consisting essentially of WCYKLPDRVSI-X12-X13-X14-G-X16-CN;
- wherein
- X12 is K or E;
- X13 is R or E;
- X14 is R or K;
- and
- X16 is R or K;
- and
- wherein the venom-based peptide is 18 amino acids in length.
Dependencies are inferred from the claim text.