Loading patent…
AssigneeChugai Seiyaku Kabushiki Kaisha
InventorsAtsushi Kimbara, Takeo Harada, Susumu Komiyama, Mizuki Okuyama, Yoshihito Ohtake, Yoshihisa Murata, Rie Saito
Estimating the term…
Provided is a low-molecular compound or a salt thereof, or a solvate thereof which has the ability to activate Nrf2. The present invention provides a compound represented by the formula (1) or a salt thereof, or a solvate thereof, wherein Xa1 is CRa1 or N, Xa3 is CRa3 or N, Ra1, Ra2 and Ra3 are each independently selected from the group consisting of hydrogen, halogen and C1-C6 alkoxy, Xb1, Xb2 and Xb3 are each independently selected from the group consisting of CH2, O, NH, S and C═O, Y is C6-C10 aryl optionally having a substituent or 5- to 10-membered heteroaryl optionally having a substituent, and Z is C6-C10 aryl optionally having a substituent, 5- to 10-membered heteroaryl optionally having a substituent or C1-C6 alkyl optionally having a substituent.
A compound selected from the following compounds, or a salt thereof, or a solvate thereof:
Dependencies are inferred from the claim text.