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US 12,441,678 B2Granted
Sphingolipid, and dermatologic composition comprising same for external application
AssigneeCroda Korea Ltd
InventorsKwanhyoung Lee, Ara Kim, Jihye Han, Sojung Lim, Juyeon Lee, Heesun Kim, Youngbeom Kim, Daebang Seo
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Abstract
A novel sphingolipid is disclosed. The novel sphingolipid is in liquid form at room temperature due to a low melting point, and blends easily with a variety of vegetable and/or animal oils. A dermatologic composition for external application containing the novel sphingolipid is also disclosed. The composition is useful in providing anti-inflammatory protection, improving moisturization, protecting the skin from ultraviolet (UV) light, or enhancing skin barriers.
Claims19
A sphingolipid represented by Chemical Formula 1:
- wherein:
- R1 is CH2—CH2, CH═CH, or C(H) R4—CH2;
- R2 is a saturated or unsaturated aliphatic hydrocarbon group of 12 to 28 carbon atoms;
- R3 is a saturated or unsaturated aliphatic hydrocarbon group of 12 to 28 carbon atoms substituted or unsubstituted with a hydroxyl group;
- and
- a plurality of R4's are the same as or different from each other and are each independently an aliphatic acyl group of 1 to 6 carbon atoms or a hydroxyl (OH) group,
- provided that at least one of the plurality of R4's contains at least an aliphatic acyl group of 1 to 6 carbon atoms.
4 more elements
Dependencies are inferred from the claim text.