Back to results
US 12,440,833 B2Granted
Sample containers adapted for acoustic ejections and sample preservation and methods thereof
AssigneeLabcyte Inc.
InventorsRichard N. Ellson, Joseph D. Olechno, Robert G. Kuimelis
Life of this patent
Estimating the term…
Abstract
Sample container for holding and transferring a liquid sample and method thereof. The sample container includes an inlet configured to allow a liquid sample to enter a sample container, and an outlet configured to allow one or more droplets of the liquid sample to exit the sample container by one or more acoustic ejections respectively. The inlet and the outlet are in different locations.
Claims8
A sample container for holding a liquid sample and enabling acoustic droplet ejection from the sample container, the sample container comprising:
- a liquid sample comprising a plurality of components in a liquid, each-component having a component density;
- an inlet through which the liquid sample can enter the sample container;
- an outlet through which droplets of the liquid sample can be transferred out of the sample container by one or more acoustic ejections, wherein the inlet and the outlet are in different locations;
- a side surface that allows acoustic coupling between the sample container and an acoustic generator and focusing of an acoustic beam to a focal point within the liquid sample, wherein the outlet is opposite to the side surface and the container is configured to allow acoustic ejection of the droplets of the liquid sample through the outlet when the side surface is placed in the horizontal orientation;
- and
- a plurality of acoustically uniform floats each having a float density selected to match the component density of a corresponding component in the liquid sample and including a collection region comprising a depression region in which the liquid sample containing the density-matched component is collected and from which droplets of the liquid sample containing the density-matched component can be acoustically ejected through the outlet using an acoustic radiation generator when the collection region and the acoustic radiation generator are aligned with the outlet.
3 more elements
Dependencies are inferred from the claim text.