# US 12,440,676 B2 · Implanted pulse generators with reduced power consumption via signal strength/duration characteristics, and associated systems and methods

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- Number: US 12,440,676 B2
- Document ID: US12440676B2
- Status: Granted
- Kind: B2
- Application number: 18/452,485
- Filed: 2023-08-18
- Published: 2024-05-30
- Granted: 2025-10-14
- Earliest claimed: 2014-05-20
- Assignees: Nevro Corporation
- Applicants: Nevro Corp.
- Inventors: Jon Parker
- Web page: https://patentgrep.com/patent/US12440676B2

## CPC

- A61N 1/36071: {Pain}
- A61N 1/36125: {Details of circuitry or electric components}
- A61N 1/36171: {Frequency}
- A61N 1/36175: {Pulse width or duty cycle}
- A61N 1/3708: {for power depletion}
- A61N: ELECTROTHERAPY; MAGNETOTHERAPY; RADIATION THERAPY; ULTRASOUND THERAPY (measurement of bioelectric currents A61B; surgical instruments, devices or methods for transferring non-mechanical forms of energy to or from the body A61B18/00; anaesthetic apparatus in general A61M; incandescent lamps H01K; infrared radiators for heating H05B)

## Abstract

Implanted pulse generators with reduced power consumption via signal strength-duration characteristics, and associated systems and methods are disclosed. A representative method for treating a patient in accordance with the disclosed technology includes receiving an input corresponding to an available voltage for an implanted medical device and identifying a signal delivery parameter value of an electrical signal based on a correlation between values of the signal delivery parameter and signal deliver amplitudes. The signal deliver parameter can include at least one of pulse width or duty cycle. The method can further include delivering an electrical therapy signal to the patient at the identified signal delivery parameter value using a voltage within a margin of the available voltage.

## Claims

### Claim 1

A method of programming a signal generator to provide stimulation therapy to a patient, the method comprising:
programing the signal generator to, in response to a determination that an available voltage is insufficient to deliver an electrical signal at a target therapy amplitude and a target signal delivery parameter, (a) determine an updated therapy amplitude and an updated signal delivery parameter based on pre-established correlations for similarly situated patients, and (b) deliver therapy to the patient using the updated amplitude and signal delivery parameter, wherein the signal delivery parameter includes a pulse width and/or a duty cycle.

### Claim 2 (depends on 1)

The method of claim 1 wherein the signal delivery parameter is the pulse width.

### Claim 3 (depends on 2)

The method of claim 2 wherein the pre-established correlations include a plurality of predetermined pulse width/amplitude pairs determined using data from the similarly situated patients.

### Claim 4 (depends on 2)

The method of claim 2 wherein the updated pulse width has a value within a pulse width range off rom 10 microseconds to 333 microseconds.

### Claim 5 (depends on 1)

The method of claim 1 wherein the signal delivery parameter is the duty cycle.

### Claim 6 (depends on 5)

The method of claim 5 wherein the pre-established correlations include a plurality of predetermined duty cycle/amplitude pairs determined using data from the similarly situated patients.

### Claim 7 (depends on 5)

The method of claim 5 wherein the updated duty cycle has a value within a duty cycle range off rom 10% to 100%.

### Claim 8 (depends on 1)

The method of claim 1 wherein the similarly situation patients and the patient have the same indication.

### Claim 9 (depends on 1)

The method of claim 1 wherein the available voltage is an output voltage of a battery that provides power for generating the electrical signal.

### Claim 10 (depends on 1)

The method of claim 1 wherein the electrical signal has a frequency in a frequency range of from 1.5 kHz to 100 kHz.

### Claim 11 (depends on 1)

The method of claim 1 wherein the electrical signal does not induce paresthesia in the patient.

### Claim 12

A system for providing stimulation therapy to a patient, the system comprising:
a signal generator programmed to deliver an electrical signal to the patient; a processor; and
a memory storing instructions that, when executed by the processor, cause the signal generator to, in response to a determination that an available voltage is insufficient to deliver the electrical signal at a target therapy amplitude and a target signal delivery parameter, (a) determine an updated therapy amplitude and an updated signal delivery parameter based on pre-established correlations for similarly situated patients, and (b) deliver therapy to the patient using the updated amplitude and signal delivery parameter, wherein the signal delivery parameter includes a pulse width and/or a duty cycle.

### Claim 13 (depends on 12)

The system of claim 12 wherein the signal delivery parameter is the pulse width, and wherein the pre-established correlations include a plurality of predetermined pulse width/amplitude pairs determined using data from the similarly situated patients.

### Claim 14 (depends on 12)

The system of claim 12 wherein the signal delivery parameter is the duty cycle, and wherein the pre-established correlations include a plurality of predetermined duty cycle/amplitude pairs determined using data from the similarly situated patients.

### Claim 15 (depends on 12)

The system of claim 12 wherein the similarly situation patients and the patient have the same indication.

### Claim 16

A method of establishing a correlation between an amplitude and another signal delivery parameter for a particular patient, the method comprising:
identifying at least one amplitude/parameter pair that produces a detectable result in the patient; and
comparing the identified amplitude/parameter pair to a plurality of pre-established amplitude/parameter curves generated using data from a pool of other patients to identify a particular amplitude/parameter curve for the patient, wherein the signal delivery parameter includes a pulse width and/or a duty cycle.

### Claim 17 (depends on 16)

The method of claim 16 wherein identifying the at least one amplitude/parameter pair includes identifying a plurality of amplitude/parameters pairs and wherein comparing the identified amplitude/parameter pair includes comparing the plurality of identified amplitude/parameter pairs to the curves.

### Claim 18 (depends on 16)

The method of claim 16 wherein the signal delivery parameter is the pulse width, and wherein the pre-established amplitude/parameter curves generated using data from the pool of other patients include specific amplitude/pulse width pairs.

### Claim 19 (depends on 18)

The method of claim 18, further comprising delivering an electrical signal to the patient, wherein the electrical signal has an amplitude and a pulse width corresponding to a specific amplitude/pulse width pair on the identified particular amplitude/parameter curve.

### Claim 20 (depends on 16)

The method of claim 16 wherein the signal delivery parameter is the duty cycle, and wherein the pre-established amplitude/parameter curves generated using data from the pool of other patients include specific amplitude/duty cycle pairs.

### Claim 21 (depends on 20)

The method of claim 20, further comprising delivering an electrical signal to the patient, wherein the electrical signal has an amplitude and a duty cycle corresponding to a specific amplitude/duty cycle pair on the identified particular amplitude/parameter curve.

### Claim 22 (depends on 16)

The method of claim 16 wherein the pool of other patients have the same indication as the particular patient.
