Microplegia delivery system
AssigneeTerumo Cardiovascular Systems Corporation
InventorsCarmen Joseph Leone, Paul Thomas Kotnik
Life of this patent
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Abstract
Microplegia systems describe herein use syringe pumps that are controlled in a coordinated fashion to deliver cardioplegia medications during an open-heart surgery at the prescribed dosages and/or rates. The microplegia systems link the delivery rate of the syringe pumps with the delivery rate of the cardioplegia blood flow rate. A perfusionist can enter prescribed drug concentrations, desired ratios between drug and blood, and the expected dose for each phase of the myocardial protection scheme that will take place during the open-heart surgery. Additionally, or alternatively, the syringe pump systems described herein can also be used to deliver other non-cardioplegia types of therapeutic substances.
Claims20
A heart/lung bypass machine system comprising:
- a heart/lung machine comprising:
- an arterial blood pump;
- and
- a cardioplegia blood pump;
- a first cardioplegia agent syringe pump configured to inject a first cardioplegia agent at a first location along a blood/cardioplegia supply line;
- a second cardioplegia agent syringe pump configured to inject a second cardioplegia agent at a second location along the blood/cardioplegia supply line, wherein the first and second locations are longitudinally spaced apart from each other;
- and
- a controller comprising a hardware processor and computer memory, the controller in electrical signal communication with the cardioplegia blood pump and the first and second cardioplegia agent syringe pumps,
- wherein the controller is configured to modulate operational speeds of the first and second cardioplegia agent syringe pumps based on an actual speed of the cardioplegia blood pump and based on a current surgery phase of at least three different phases of surgery,
- wherein the at least three different phases of surgery comprise:
- (i) an induction dose phase, (ii) a maintenance dose phase, and (iii) a reperfusion or reanimation dose phase,
- wherein the controller is configured to receive user inputs that correlate the operational speeds of the first and second cardioplegia agent syringe pumps to the actual speed of the cardioplegia blood pump,
- wherein the user inputs are percentages of the actual speed of the cardioplegia blood pump,
- wherein the controller is configured to issue a time-based reminder to collect a blood sample for an activated clotting time (“ACT”) lab test and to allow for entry of results of the ACT lab test, and
- wherein the controller is configured to suggest a dose adjustment based on:
- (i) the results of the ACT lab test, (ii) a user-established ACT target value, and (iii) one or more patient parameters.
A method of operating a heart/lung machine system, the method comprising:
- receiving, by a controller of the heart/lung machine system, user inputs indicative of prescribed correlations between a speed of a cardioplegia blood pump and (i) a speed of a first cardioplegia agent syringe pump and (ii) a speed of a second cardioplegia agent syringe pump;
- modulating, by the controller of the heart/lung machine system, the speed of the first cardioplegia agent syringe pump based on:
- (i) an actual speed of the cardioplegia blood pump, (ii) the user input indicative of the prescribed correlation between the speed of the cardioplegia blood pump and the speed of the first cardioplegia agent syringe, and (iii) a current surgery phase of at least three different phases of surgery;
- issuing, by the controller, a time-based reminder to collect a blood sample for an activated clotting time (“ACT”) lab test;
- receiving, by the controller, a user entry of results of the ACT lab test;
- suggesting, by the controller, a dose adjustment based on:
- (i) the results of the ACT lab test, (ii) a user-established ACT target value, and (iii) one or more patient parameters;
- and
- modulating, by the controller of the heart/lung machine system, the speed of the second cardioplegia agent syringe pump based on:
- (i) the actual speed of the cardioplegia blood pump, (ii) the user input indicative of the prescribed correlation between the speed of the cardioplegia blood pump and the speed of the second cardioplegia agent syringe pump, and (iii) the current surgery phase of at least three different phases of surgery,
- wherein the user inputs are percentages of the actual speed of the cardioplegia blood pump, and
- wherein the at least three different phases of surgery comprise:
- (i) an induction dose phase, (ii) a maintenance dose phase, and (iii) a reperfusion or reanimation dose phase.
Dependencies are inferred from the claim text.