Circumferentially sensing manometry systems and methods with catheter utilizing pressure sensitive mems

A manometry system comprising:

• manometric catheter probe comprising:
• a flexible printed circuit;
• at least one pressure sensor assembly coupled with the flexible printed circuit along a length of the flexible printed circuit, the at least one pressure sensor assembly including:
• a body including an annular recess;
• a central cavity through the body receiving at least a portion of the flexible printed circuit;
• a pressure balloon disposed on an outside of the central cavity, including:
• a fluid configured to communicate pressure to a microelectromechanical systems (MEMS) sensor;
• and
• a first flexible sleeve disposed over the body in a manner forming a cavity between the first flexible sleeve and the annular recess for containing the fluid;
• a MEMS sensor disposed in the pressure balloon, in communication with the fluid;
• and
• an electrical connector configured to electrically couple the MEMS sensor and the flexible printed circuit;
• and
• a second sleeve disposed over the at least one pressure sensor assembly;
• a processor;
• and
• a memory, including instructions stored thereon, which, when executed, cause the manometry system to:
• acquire a pressure measurement from the at least one pressure sensor assembly, and
• determine, based on the measurements, at least one of a motility function of an esophagus or a bolus transit dynamics in the esophagus.

A manometric catheter sensor assembly, comprising:

• a body including:
• a central cavity;
• and
• an annular recess around the body;
• a microelectromechanical systems (MEMS) sensor disposed in the annular recess of the body;
• an electrical connector configured to electrically couple the MEMS sensor and a flexible printed circuit;
• a first flexible sleeve disposed over the body in a manner forming a cavity between the first flexible sleeve and the annular recess of the body for containing a fluid, the first flexible sleeve includes the fluid configured to communicate pressure to the MEMS sensor;
• a first sealing channel disposed on a first end of the body and configured to seal the fluid in the first flexible sleeve;
• a second sealing channel disposed on a second end of the body and configured to seal the fluid in the first flexible sleeve;
• and
• a second sleeve disposed over the MEMS sensor.

A manometric catheter probe kit, comprising:

• a flexible printed circuit;
• at least one pressure sensor assembly including:
• a body including a central cavity configured to receive at least a portion of the flexible printed circuit;
• an annular recess around the body;
• a microelectromechanical systems (MEMS) sensor configured to be disposed in the annular recess;
• an electrical connector configured to electrically couple the MEMS sensor and the flexible printed circuit;
• and
• a first flexible sleeve configured to be disposed over the body in a manner forming a cavity between the first flexible sleeve and the annular recess for containing a fluid, the first flexible sleeve including the fluid configured to communicate pressure to the MEMS sensor;
• and
• a second sleeve configured to be disposed over the at least one pressure sensor assembly.