Hyperimmunized egg product for treating or preventing alcoholic liver disease and graft- versus-host disease
AssigneeProdigy Biotech
InventorsSubramanian V. Iyer, Sunny Patel
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AssigneeProdigy Biotech
InventorsSubramanian V. Iyer, Sunny Patel
Estimating the term…
In one aspect, the present disclosure is directed to a method for preventing or treating alcoholic liver disease or graft-versus-host disease in a subject in need thereof, comprising administering to the subject a therapeutically effective amount of a hyperimmunized egg product obtained from an egg-producing animal, thereby preventing or treating the alcoholic liver disease or the graft-versus-host disease in the subject, wherein the hyperimmunized egg product comprises a therapeutically effective amount of one or more antibodies to an antigen selected from the group consisting of Enterococcus faecalis, Enterococcus faecalis cytolysin toxin, and Enterococcus faecium. The present disclosure is also directed to hyperimmunized eggs and egg products produced by an animal that has been hyperimmunized with an antigen selected from the group consisting of Enterococcus faecalis, isolated Enterococcus faecalis cytolysin toxin, and Enterococcus faecium. Methods of preparing the hyperimmunized eggs and egg products are also disclosed.
A hyperimmunized egg produced by an animal that has been hyperimmunized with an antigen selected from the group consisting of Enterococcus faecalis that expresses cytolysin toxin, and isolated Enterococcus faecalis cytolysin toxin, wherein the level of antibodies to the Enterococcus faecalis cytolysin toxin in the hyperimmunized egg is increased relative to an egg from an animal that has not been hyperimmunized, and wherein the titer of antibodies to Enterococcus faecalis cytolysin toxin in the hyperimmunized egg is at least 8000.
Dependencies are inferred from the claim text.