Cocrystals of posaconazole, methods of making and using same
AssigneeThe Regents of the University of Michigan
InventorsNaír Rodriguez-Hornedo, Gislaine Kuminek, Katie L. Cavanagh
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Abstract
The disclosure generally relates to cocrystals of posaconazole and a coformer. The disclosure further relates to pharmaceutical compositions comprising the cocrystals, as well as methods of making the cocrystals, and methods of treating or preventing fungal, yeast, or dermatophyte infections using the cocrystals.
Claims6
A cocrystal comprising posaconazole and a coformer, wherein the coformer comprises 4-aminobenzoic acid (4ABA), characterized by an X-ray powder diffraction (XRPD) pattern comprising peaks at 5.8, 10.3, 11.5, 18.9, 19.3, 21.7, 22.4±0.2° 2θ using Cu Kα radiation.
Dependencies are inferred from the claim text.