Methods for the treatment of neurological disorders
AssigneeJanssen Pharmaceutica NV
InventorsBenjamin Matteson Vincent, Daniel Forrest Tardiff, Jeff Scott Piotrowski, Eric Solis, Robert Hughie Scannevin, Chee-Yeun Chung, Rebecca Aron, Bertrand Le Bourdonnec, Matthew Lucas, Kenneth Rhodes
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Abstract
The present disclosure provides compounds and methods useful in the treatment of neurological disorders. The compounds of the invention, alone or in combination with other pharmaceutically active agents, can be used for treating or preventing neurological disorders.
Claims23
A method of treating a neurological disorder in a subject in need thereof, the method comprising administering an SCD inhibitor in an amount sufficient to suppress toxicity in a cell related to protein misfolding or aggregation, wherein the SCD inhibitor is selected from the group consisting of:
A method of suppressing toxicity in a cell related to protein misfolding or aggregation in a subject, the method comprising contacting a cell with an SCD inhibitor, wherein the SCD inhibitor is selected from the group consisting of:
Dependencies are inferred from the claim text.