Monitoring device for temperature-controlled capillary guidance having nested tubes and transport capillaries for NMR flow cells

Abstract

A monitoring device (100) for performing a measurement of a reaction liquid (102) produced in a reaction tank (101) in an NMR spectrometer (103), the device comprising the following components: a hollow NMR sample probe (104) for receiving the reaction liquid to be measured; an inlet transport capillary (105) for receiving the reaction liquid from the reaction tank and for transport from the reaction tank via a pump device (106) to the sample probe; an outlet transport capillary (108) for the return transport of the reaction liquid from the sample probe to the reaction tank; a device (10) for conducting temperature-control fluid (25) around the inlet and outlet transport capillaries, the device for conducting temperature control-fluid comprising tube portions (23), each of which is constructed in double-walled fashion from two radially closed partial tubes arranged nested in one another, comprising an outer partial tube (19) and an inner partial tube (21), the temperature-control fluid flowing between the outer and the inner partial tube, and the inlet transport capillary or the outlet transport capillary being arranged radially within the inner partial tube, is characterized in that the monitoring device has a closed temperature-control circuit for the temperature-control fluid, which circuit is geometrically designed such that the temperature-control fluid always flows only in a predetermined direction in each spatial region of the temperature-control circuit and no opposing flow of the temperature-control fluid in the immediate vicinity of the spatial region occurs. As a result, the reaction liquid is constantly and completely temperature-controlled in a uniform manner over its entire transport path.

Dependencies are inferred from the claim text.