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US 12,429,490 B2Granted
Optical reader for analyte testing
AssigneeAspida Dx Inc.
InventorsAshutosh Shastry, David Piehler, Hardeep Sanghera, Michael Gluzczack, Pranav Chopra, Yun-Pei Chang, Ameya Kantak
Life of this patent
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Abstract
Analyte collection and testing systems and methods, and more particularly to disposable oral fluid collection and testing systems and methods. Described herein are methods and apparatuses to achieve significant improvements in the detection of fluorescence signals in the reader.
Claims20
An optical reader system, the system comprising
- a reader housing including a cartridge holder configured to receive a cartridge comprising a photonic chip within a slot of the cartridge holder;
- a scan head within the reader housing and configured to move relative to the cartridge holder, wherein the scan head comprises a first plurality of optical fiber ends optically connected to one or more laser light sources and a second plurality of optical fiber ends optically connected to a plurality of detectors;
- one or more processors;
- and
- a memory storing computer-program instructions that, when executed by the one or more processors, cause the system to perform a method comprising;
- aligning the scan head with the photonic chip so that the photonic chip and the first plurality of optical fiber ends are aligned along a polarization axis with the chip;
- maintaining a polarization of the polarization axis in a transverse-magnetic (TM) polarization;
- and
- emitting one or more beams of light from the one or more laser light sources through the first plurality of optical fiber ends and into an edge of the photonic chip in the TM polarization;
- and
- detecting TM polarized light from one or more waveguides within the chip using the scan head when the one or more beams of light interact with an analyte molecule on the chip.
8 more elements
An optical reader system, the system comprising
- a reader housing including a cartridge holder configured to receive a cartridge comprising a photonic chip within a slot of the cartridge holder;
- a scan head within the reader housing configured to move relative to the cartridge holder, wherein the scan head comprises a first plurality of optical fiber ends optically connected to one or more laser light sources and a second plurality of optical fiber ends optically connected to a plurality of detectors;
- one or more processors;
- and
- a memory storing computer-program instructions that, when executed by the one or more processors, cause the system to perform a computer-implemented method comprising;
- aligning the scan head with the photonic chip so that the photonic chip and the one or more laser light sources, and the first plurality of optical fiber ends are aligned along a polarization axis with the chip;
- maintaining a polarization of the polarization axis in a transverse-magnetic (TM) polarization;
- and
- emitting one or more beams of light from the one or more laser light sources, through the first plurality of optical fiber ends and into an edge of the photonic chip in the TM polarization;
- and
- detecting, using the second plurality of optical fiber ends, TM polarized light from one or more waveguides within the chip when the one or more beams of light interact with an analyte molecule on the chip.
8 more elements
Dependencies are inferred from the claim text.