Sorbent for a dialysis device and dialysis system
AssigneesTemasek Polytechnic, Awak Technologies Pte Ltd
InventorsChristian Gert Bluchel, Peter Haywood
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Abstract
The invention relates to a sorbent for removing metabolic waste products from a dialysis liquid, the sorbent comprising a soluble source of sodium ions. The sorbent comprises an ion exchange system which converts urea to ammonium ions and which is configured to exchange ammonium ions for predominantly hydrogen ions and to exchange Ca, Mg, and K for predominantly sodium ions. The soluble source of sodium ions overcomes an initial drop in sodium concentration in regenerated dialysate. When used in conjunction with an infusion system configured to utilise exchange of Ca, Mg and K for sodium during dialysate regeneration a desired sodium ion concentration can be maintained.
Claims8
A sorbent for removing metabolic waste products from a dialysis liquid, wherein the sorbent comprises a homogeneous mixture of:
- (a) uremic toxin-treating enzyme particles comprising a uremic toxin-treating enzyme immobilized on a solid support that hydrolyses urea to ammonium and bicarbonate ions;
- (b) cation exchange particles set to a pH range of from 3.5 to 5.0,
- wherein the cation exchange particles are configured to bind ammonium ions in exchange for protons, and bind calcium, magnesium, and/or potassium ions in exchange for sodium ions;
- (c) anion exchange particles;
- and
- (d) a soluble source of sodium ions.
Dependencies are inferred from the claim text.