Methods for treating respiratory distress and compositions for use in the same
OwnerJohn E. Boydinventor
Life of this patent
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Abstract
Methods for treating respiratory distress such as ARDS using foaming agent(s) (e.g., natural and/or synthetic surfactant(s)) and/or external energy (e.g., vibration, acoustic, etc.) and compositions and systems configured for performing the same.
Claims20
A method of treating an individual having at least one lower respiratory system region with at least one respiratory symptom, the method comprising:
- (a) administering at least one foaming agent to the at least one lower respiratory system region, wherein the at least one lower respiratory system region includes at least one alveolus having excess alveolar edema fluid;
- and
- (b) applying external energy to the at least one lower respiratory system region including to at least one alveolus in an effective amount and for an effective time period to generate bubbles and/or foam within the at least one lower respiratory system region to reduce the amount of excess alveolar edema fluid within the at least one alveolus.
A method of treating an individual having at least one lower respiratory system region with acute respiratory distress syndrome (ARDS) symptoms including at least one alveolus having excess alveolar edema fluid, the method comprising administering at least one foaming agent and applying external energy to the at least one lower respiratory system region in an effective amount and for an effective time period to generate bubbles and/or foam within the at least one lower respiratory system region to reduce at least one of said acute respiratory distress syndrome (ARDS) symptoms.
A method of treating an individual having at least one lower respiratory system region with acute respiratory distress syndrome (ARDS) symptoms, the method comprising:
- (a) administering one or more lung surfactants and/or one or more pulmonary surfactants to the at least one lower respiratory system region, wherein the at least one lower respiratory system region includes at least one alveolus having excess alveolar edema fluid;
- (b) applying sound wave and/or vibrational energy to the at least one lower respiratory system region including to the at least one alveolus in an effective amount and for an effective time period to reduce the amount of excess alveolar edema fluid within the at least one alveolus;
- and
- (c) removing excess alveolar edema fluid from the at least one lower respiratory system region,
- wherein the method results in increased oxygen/carbon dioxide exchange within the at least one lower respiratory system region.
Dependencies are inferred from the claim text.