US 12,427,194 B2 · Composition and methods for treating acute diarrhea and enteric

Abstract

The composition may be used therapeutically or prophylactically and is directed toward a cluster of diarrhea-causing pathogens which cause illness or death in animals, including dogs and cats. It is prepared from a powdered egg preparation and powdered protein matrix, such as bovine colostrum. The eggs are collected from hens which have been immunized with the relevant pathogens or toxins. When the matrix includes colostrum, the powdered colostrum is derived from non-hyperimmune cattle. The vaccination strategy includes the use of antibody cross-reactivity between toxins or pathogens which cause diarrhea. For some diseases, including canine parvo, the clinical improvement using this therapeutic exceeds the standard of care. Instead of a pharmaceutical product, this composition is an orally administered food product with the same safety profile as eggs and milk.

Claims18

Dependent claims

A composition for treatment or prevention of diarrhea or enteric infection in animals, the composition comprising:

a. a mixture of IgY antibodies specific for a plurality of antigens obtained from a plurality of organisms, wherein the organisms cause diarrhea in animals, and wherein a mercury content in the mixture is less than 0.001 ppm;
and
b. a protective matrix comprising protein, wherein the protein is derived from a non-hyperimmune animal source and comprises at least 20 percent of the composition by weight.

A method comprising:

a. providing a mixture of IgY antibodies specific for a plurality of antigens obtained from a plurality of organisms, wherein the organisms cause diarrhea in animals, wherein a mercury content in the mixture is less than 0.001 ppm and wherein one of the organisms is parvovirus;
b. combining the mixture of IgY antibodies with a protective matrix comprising protein, wherein the combining results in a composition, and wherein the protein is derived from a non-hyperimmune animal source and comprises at least 20 percent of the composition by weight;
and
c. treating a sick animal using the composition, the treatment comprising:
administering the composition to a sick animal infected with at least one of the organisms;
monitoring one or more symptoms of the sickness;
and
establishing an efficacy of the composition based on an absence of the symptoms and an eradication of the sickness in the animal based on testing.

5 more elements

Dependencies are inferred from the claim text.

Composition and methods for treating acute diarrhea and enteric

Life of this patent

Composition and methods for treating acute diarrhea and enteric

Life of this patent

Abstract

Claims18