Probiotic compositions comprising lactobacillus reuteri strains and methods of use
AssigneeBiomEdit, Inc.
InventorsArvind Kumar, Dharanesh Mahimapura Gangaiah
Life of this patent
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Abstract
The present invention relates to probiotic compositions and methods for increasing animal health. The probiotic compositions include one or more isolated strains of novel Lactobacillus reuteri strains which colonizes the gastrointestinal tract to increase the health of an animal.
Claims31
A method for increasing animal health, the method comprising administering to an animal an effective amount of a composition comprising at least one Lactobacillus reuteri strain selected from:
- (a) an isolated first Lactobacillus reuteri strain comprising a nucleic acid sequence having at least 99% sequence identity with SEQ ID NO:26, and further having a nucleic acid sequence having at least 99% sequence identity with SEQ ID NO:
- 1, a nucleic acid sequence having at least 99% sequence identity with SEQ ID NO:
- 3, and a nucleic acid that encodes for an amino acid sequence having at least 99% sequence identity with SEQ ID NO:
- 8;
- and
- (b) an isolated second Lactobacillus reuteri strain comprising a nucleic acid sequence having at least 99% sequence identity with SEQ ID NO:25, and further having a nucleic acid sequence having at least 99% sequence identity with SEQ ID NO:
- 27, a nucleic acid sequence having at least 99% sequence identity with SEQ ID NO:
- 28, and a nucleic acid sequence having at least 99% sequence identity with SEQ ID NO:
- 29;
- wherein said composition increases animal health when an effective amount is administered to an animal, as compared to an animal not administered the composition.
A method of treating, ameliorating the effects of, or preventing necrotic enteritis in poultry by administering to a poultry in need thereof a composition comprising at least one Lactobacillus reuteri strain selected from:
- (a) an isolated first Lactobacillus reuteri strain comprising a nucleic acid sequence having at least 99% sequence identity with SEQ ID NO:26, and further having a nucleic acid sequence having at least 99% sequence identity with SEQ ID NO:
- 1, a nucleic acid sequence having at least 99% sequence identity with SEQ ID NO:
- 3, and a nucleic acid that encodes for an amino acid sequence having at least 99% sequence identity with SEQ ID NO:
- 8;
- and
- (b) an isolated second Lactobacillus reuteri strain comprising a nucleic acid sequence having at least 99% sequence identity with SEQ ID NO:25, and further having a nucleic acid sequence having at least 99% sequence identity with SEQ ID NO:
- 27, a nucleic acid sequence having at least 99% sequence identity with SEQ ID NO:
- 28, and a nucleic acid sequence having at least 99% sequence identity with SEQ ID NO:
- 29.
Dependencies are inferred from the claim text.