An ion storage system based on a quadrupole-ion trap tandem mass spectrometry, comprising a heating capillary, a tube lens, a skimmer, a first ion guide, a second ion guide, a quadrupole mass analyzer, an ion trap mass analyzer, and a detector that are sequentially arranged, wherein a first lens disposed between the first ion guide and the second ion guide;
- and a second lens and a third lens are disposed between the second ion guide and the quadrupole mass analyzer,
- wherein the first ion guide is a quadrupole for collisional focusing and transmission of ions in second-stage vacuum, and
- wherein the second ion guide is a quadrupole for collisional focusing and transmission of ions in third-stage vacuum.