Oligosaccharide, preparation method therefor, composition thereof and use thereof
AssigneeYantai Dongcheng Biochemicals Co., Ltd
InventorsZhongjun Li, Xiaoming Wu, Xiao Zhang, Huiying Liu, Wang Yao, Qingbao Yang, Jianqiang Wang, Tian He
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Abstract
A fucosylated chondroitin sulfate oligosaccharide having the structure as shown in J, and further disclosed is a method for preparing the fucosylated chondroitin sulfate oligosaccharide: using a chondroitin sulfate A salt as a raw material, sequentially performing enzymolysis, a group protection operation, and glycosylation to synthesize the oligosaccharide compound; the certainty of the described structure allows said oligosaccharide to be applied to the medical field.
Claims15
A fucosylated chondroitin sulfate oligosaccharide shown as Formula J, wherein:
- in Formula J, Ac is acetyl;
- q is a positive integer and q≤10;
- Y is H, alkali metal, alkaline earth metal, or N(R6)4, wherein R6 is C1-C4 alkyl;
- R is azido, C1-C4 alkoxy, phenoxy, C1-C4 alkylthio, C1-C4 alkanoylthio, benzoyloxy or benzoylthio.
Dependencies are inferred from the claim text.