Cystic fibrosis transmembrane conductance regulator modulating agents

A process for preparing Compound I, comprising reacting compound 8:

• with compound 3:
• to produce Compound I:

A process for preparing Compound Ia:

• comprising converting compound 20:
• into compound Ia.

A process for preparing Compound Ib:

• comprising converting compound 22:
• into compound Ib.

A process for preparing Compound Ic:

• comprising converting compound 23:
• into compound Ic.

A process for preparing Compound Id:

• comprising converting compound 35:
• into compound Id.

A compound selected from compound 8:

• a deuterated derivative thereof, and a pharmaceutically acceptable salt of any of the foregoing.