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US 12,420,086 B2Granted
Method of manufacturing nerve electrode
AssigneeUniversity-Industry Cooperation Group of Kyung Hee University
InventorsIl Keun Kwon, Dong Nyoung Heo, Dong Hyun Lee, Sang Jin Lee, Min Heo
Life of this patent
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Abstract
The present invention relates to a method of manufacturing a nerve electrode in which a conductive ink is inkjet printed on an electrospun polyimide fibrous sheet; and a nerve electrode manufactured by the manufacturing method.
Claims7
A method of manufacturing a nerve electrode for sensing nerve signals, the method comprising the steps of:
- 1) manufacturing a poly (amic acid) fibrous sheet by electrospinning poly (amic acid), wherein the poly (amic acid) is synthesized by polycondensation of pyromellitic dianhydride (PMDA) and 4,4′-oxydianiline in N,N-dimethylacetamide, and the polycondensation of the PMDA and the 4,4′-oxydianiline in the N,N-dimethylacetamide is performed under a temperature equal to or less than 4° C. for more than one hour;
- 2) manufacturing a polyimide fibrous sheet by heat-treating the poly (amic acid) fibrous sheet at a temperature of 300° C. to 400° C.;
- 3) thermally compressing the polyimide fibrous sheet at a temperature of 80° C. to 140° C. under a pressure of 600,000 N/m2 to 900,000 N/m2 for 30 minutes to 6 hours;
- 4) inkjet printing a conductive ink on the polyimide fibrous sheet thermally compressed in Step 3);
- 5) heat-treating the polyimide fibrous sheet on which the conductive ink is inkjet printed in Step 4) at a temperature of 140° C. to 220° C.;
- and 6) applying poly(3,4-ethylene dioxythiophene)/poly (styrenesulfonate) (PEDOT/PSS) on the inkjet printed conductive ink by an electrochemical polymerization method, thereby enhancing the sensing of the nerve signals.
3 more elements
Dependencies are inferred from the claim text.