Surgical repair graft
AssigneeTELA Bio, Inc.
InventorE. Skott Greenhalgh
Life of this patent
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Abstract
Surgical repair grafts may include at least one biotextile layer and a bioabsorbable carrier matrix including carrier particles attached to the at least one biotextile layer. The carrier particles may include an active agent. The carrier particles may include non-concentric internally aqueous chambers each surrounded by a lipid membrane. The carrier particles may be configured to release the active agent upon exposure to an aqueous fluid. The carrier particles may be attached to the at least one biotextile layer at discrete attachment sites as islands that are spaced apart from each other to provide axial compliance to the surgical repair graft during bending of the surgical repair graft.
Claims19
A surgical repair graft comprising:
- at least one biotextile layer;
- and
- a bioabsorbable carrier matrix comprising a plurality of carrier particles attached to the at least one biotextile layer, the plurality of carrier particles comprising an active agent, wherein the plurality of carrier particles include non-concentric internally aqueous chambers each surrounded by a lipid membrane, wherein the plurality of carrier particles are configured to release the active agent upon exposure to an aqueous fluid, and wherein the plurality of carrier particles are attached to the at least one biotextile layer at discrete attachment sites as islands that are spaced apart from each other to provide axial compliance to the surgical repair graft during bending of the surgical repair graft.
A surgical repair graft comprising:
- at least one biotextile layer;
- and
- a bioabsorbable carrier matrix comprising a plurality of carrier particles attached to the at least one biotextile layer, the plurality of carrier particles comprising an active agent, wherein the plurality of carrier particles are multivesicular liposomes having non-concentric internally aqueous chambers each surrounded by a lipid membrane, wherein the plurality of carrier particles are configured to release the active agent upon exposure to an aqueous fluid, and wherein the plurality of carrier particles are attached to the at least one biotextile layer at discrete attachment sites as islands that are spaced apart from each other to provide axial compliance to the surgical repair graft during bending of the surgical repair graft,
- wherein the at least one biotextile layer comprises pores that are configured to allow a flow of the active agent from the bioabsorbable carrier matrix therethrough.
Dependencies are inferred from the claim text.