Imaging composition comprising porous silicon micro-particles
AssigneeUniversity-Industry Cooperation Group of Kyung Hee University
InventorsDokyoung Kim, Jaehoon Kim
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Abstract
The present disclosure describes an imaging composition including porous silicon microparticles, and more particularly, to a biological tissue imaging composition including a composite in which oxidized porous silicon microparticles and silver nanoparticles are combined. Since a biological tissue imaging agent of the present invention, which includes a composite of oxidized porous silicon microparticles and silver nanoparticles, continuously provides an image signal without spreading in the body as compared to conventional imaging agents, it is possible to increase surgical stability by accurately identifying target tissues in vivo in an affected area.
Claims6
A composition for imaging of biological tissue by computed tomography (CT), comprising a composite in which oxidized porous silicon microparticles and silver nanoparticles are combined,
- wherein the silver nanoparticles are bonded into pores of the oxidized porous silicon microparticles and attached to a surface of the oxidized porous silicon microparticles,
- wherein the composite is dissolved in a mixture of glycerol and water in a ratio of 3:1,
- wherein the composition has in vivo local area reactivity,
- wherein a size of the porous silicon microparticles is in a range of 1 μm to 10 μm, and
- wherein the composite includes elemental silicon, elemental oxygen, and elemental silver in a weight ratio of 100:100 to 120:15 to 30.
Dependencies are inferred from the claim text.