Phage cocktail against E. coli 0157
AssigneeMicreos Food Safety B.V.
InventorsJoël Thomas van Mierlo, Sander Witte, Steven Hagens
Life of this patent
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Abstract
The invention relates to the field of microbiology, specifically to an antimicrobial composition comprising a first and a second bacteriophage, wherein the composition has lytic activity against E. coli O157. The invention further relates to a use of the antimicrobial composition for controlling bacterial contamination in a food- or feed environment on or in food- or feed processing equipment or food- or feed containers or in a food- or feed product.
Claims14
A method of controlling bacterial contamination in a food- or feed environment or in food- or feed processing equipment or food- or feed containers or in a food- or feed product comprising contacting a composition with the food- or feed environment or the food- or feed processing equipment or the food- or feed containers or the food- or feed product, wherein the composition has lytic activity against E.coli O157 and comprises a first bacteriophage and a second bacteriophage, wherein:
- the first bacteriophage has a genome with at least 98% sequence identity with SEQ ID NO:
- 1 over the entire length of SEQ ID NO:
- 1, or
- the second bacteriophage has a genome with at least 98% sequence identity with SEQ ID NO:
- 2 over the entire length of SEQ ID NO:
- 2,
- and wherein the first bacteriophage comprises:
- a tail spike protein that has at least 97% sequence identity with SEQ ID NO:
- 3 over the entire length of SEQ ID NO:
- 3 or has at least 97% sequence identity with SEQ ID NO:
- 4 over the entire length of SEQ ID NO:
- 4, and
- a tail spike protein that has at least 97% sequence identity with SEQ ID NO:
- 5 over the entire length of SEQ ID NO:
- 5.
Dependencies are inferred from the claim text.