System and methods for continuous production of cyclodextrins from cellulose
AssigneeUnited Arab Emirates University
InventorsSulaiman Al Zuhair, Saleha Almardeai, Babatunde Ogunbadejo, Emad Elnajjar, Yaser Mohamed Greish, Boguslaw Kruczek, Bart Van Der Bruggen
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Abstract
The present invention pertains to novel system and methods for the streamlined and efficient continuous production of cyclodextrins by utilizing lignocellulosic wastes. The system comprises a tubular membrane bioreactor where enzymatic hydrolysis of cellulose into glucose is conducted continuously. The method comprises a first part where cellulose is hydrolyzed to pure glucose and a second part where the pure glucose reacts with to CGTase enzyme to obtain pure cyclodextrins.
Claims8
A system for continuous production of cyclodextrins from cellulose or lignocellulosic waste, comprising:
- a tubular membrane reactor comprising:
- (a) an inner reactor;
- (b) an outer cylinder surrounding the inner reactor;
- (c) an outlet connecting the outer reactor with a jacketed glass column;
- (d) a peristaltic pump connected to the inner reactor;
- (e) a heating tape fitted with the jacketed glass column via a thermocouple and connected to a temperature controller;
- (f) a hierarchical copper-based metal-organic framework (H-Cu-BTC);
- and
- (g) a quantitative filter paper (Grade 40) shredded into standard cellulose substrate having dimensions of about 5×5 mm,
- wherein the inner reactor comprises a polyethersulfone (PES) membrane,
- wherein the inner reactor is designed for the addition of enzymes, substrates, and lignocellulosic wastes,
- wherein the H-Cu-BTC is adapted for CGTase enzyme immobilization, and
- wherein the system is useful for the production of cyclodextrins from lignocellulosic wastes or cellulose.
Dependencies are inferred from the claim text.