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AssigneeWenzhou Institute, University of Chinese Academy Of Sciences
InventorsChangcan Shi, Xujian Li, Luqi Pan, Zhixiao Ji, Xiao Yang
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A bioflexible elastomer intestinal anastomosis stent based on a PTMC-b-PEG-b-PTMC copolymer, and a preparation method. Biocompatible degradable polymer medical materials, i.e., PTMC and PEG, are selected, an electrostatic spinning method is used for preparation, the size of an anastomosis tube can be adjusted according to the size of a human lumen, and the anastomosis tube is designed to not only be suitable for an anastomat of the small intestines and large intestines, but also suitable for an anastomotic and pre-supported lumen anastomat of an esophagus, artery, vein, etc. The anastomosis tube prepared has a thin wall and excellent elasticity, and in order to facilitate suturing by a doctor during a clinical surgical operation, the anastomosis tube is innovatively and seamlessly sleeved outside a plant cellulose tube having high hardness.
A bioflexible elastomer intestinal anastomosis stent based on poly(trimethylene carbonate)-b-polyethylene glycol-b-poly(trimethylene carbonate) (PTMC-b-PEG-b-PTMC) triblock copolymer, wherein the intestinal anastomosis stent is integrally made of a PTMC-b-PEG-b-PTMC triblock copolymer synthesized by a ring-opening polymerization method of molecular medical materials of polytrimethylene carbonate (PTMC) and polyethylene glycol (PEG);
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