Nanopore sensing device
AssigneeOxford Nanopore Technologies PLC
InventorsPing Xie, Justin Millis, Rhodri Davies
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Abstract
A nanopore sensing device comprises a planar structure provided with plural fluidic passages extending between the first and second chambers. The planar structure supports nanopores in membranes across respective passages and sensor electrodes are arranged to sense a fluidic electrical potential in respective passages between the nanopores and the second chamber. The passages comprise planar fluidic resistor portions between the sensor electrode and the second chamber, the planar fluidic resistor portions extending in a planar direction of the planar structure and being configured to form a fluidic resistor.
Claims30
A nanopore sensing device comprising:
- first and second chambers;
- a planar structure provided with plural fluidic passages extending between the first and second chambers, the planar structure being configured to support nanopores in membranes across respective passages;
- and
- sensor electrodes arranged to sense a fluidic electrical potential in respective passages between the nanopores and the second chamber,
- wherein the passages comprise planar fluidic resistor portions between the sensor electrode and the second chamber, the planar fluidic resistor portions extending in a planar direction of the planar structure and being configured to form a fluidic resistor;
- and
- wherein the resistance of each nanopore is greater than 50% of the total resistance of the corresponding passage.
Dependencies are inferred from the claim text.