Analytic method and kit for diagnosing alcohol use disorders
AssigneesCha University Industry-Academic Cooperation Foundation, Sungkwang Medical Foundation
InventorsKwang-Hyun Baek, Soo-Ji Kang
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Abstract
Provided is an analytical method for providing information necessary for a diagnosis of alcohol use disorder, including measuring (i) an expression level of a gene encoding a JNK or p-JNK protein in a subject's sample, (ii) an expression level of a gene encoding a JNK or p-JNK protein and an expression level of a gene encoding the Elk-1 protein in a subject's sample, or (iii) expression levels of genes encoding JNK, p-JNK, and Elk-1 proteins in a subject's sample, respectively; and a kit for a diagnosis of alcohol use disorder which is used in the analytical method.
Claims1
An analytical method for providing information necessary for a diagnosis and treatment of alcohol use disorder in a subject in need thereof, comprising
- (a) measuring expression levels of JNK, p-JNK, and Elk-1 proteins in a serum sample of a subject,
- (b) diagnosing the subject as having alcohol use disorder, wherein the diagnosis is based on a finding that the expression levels are 1.3 or more times higher in the subject compared to those of a person without alcohol use disorder, and
- (c) providing the subject having alcohol use disorder with psychological support,
- wherein the measuring is performed with antibodies capable of measuring the expression levels of JNK, p-JNK, and Elk-1 proteins.
Dependencies are inferred from the claim text.