Phosphoenolpyruvate carboxylase variant and method for producing 5à ¢â,¬â,,¢-inosinic acid using same
AssigneeDaesang Corporation
InventorsSun Hee Lee, Tae Yeol Choi, Hyun Ho Kim, Dong Hyun Kim, Hyun Sook Kim, Jong Hwan Shin
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Abstract
The present invention relates to a novel phosphoenolpyruvate carboxylase variant and a method of producing 5′-inosinic acid using the same. The phosphoenolpyruvate carboxylase variant is obtained by substituting one or more amino acids in the amino acid sequence constituting phosphoenolpyruvate carboxylase to change the activity of the protein, and a recombinant microorganism comprising the phosphoenolpyruvate carboxylase variant is capable of efficiently producing 5′-inosinic acid.
Claims8
A phosphoenolpyruvate carboxylase variant in which one or more of the amino acids at positions 472 and 673 in the amino acid sequence of SEQ ID NO:
- 4 is/are substituted with other amino acid(s).
Dependencies are inferred from the claim text.