Plant tissue-derived nanoparticles and food powders
AssigneePsigryph Inc.
InventorsGopinadhan Paliyath, Krishnaraj Tiwari, Julieta Correa-Betanzo, Priya Padmanabhan, Nagisa Nosrati, Marica Bakovic
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Abstract
Provided herein are nanoparticles including self-assembled cellular components derived from a homogenized plant tissue. Also provided are food powders and other related compositions. Methods for preparing such nanoparticles and food powders, as well as uses thereof in the treatment or prevention of diseases or disorders in a subject and/or as delivery vehicles are also described.
Claims19
A nanoparticle comprising self-assembled cellular components derived from a homogenized plant tissue derived from cherry or sour cherry, the cellular components comprising one or more structural carbohydrates or cleavage products of one or more structural carbohydrates, wherein the nanoparticle is non-crystalline and has a spherical structure with a pectin based inner core, wherein the nanoparticle is lipid-free, and
- wherein the nanoparticle comprises pectin or a cleavage product of pectin, hemicellulose or a cleavage product of hemicellulose, peptide and/or protein or a cleavage product of peptide and/or protein, an organic acid, at least one polyphenol or a cleavage product of a polyphenol, or any combination thereof.
A nanoparticle prepared by a method comprising:
- preparing a homogenized plant tissue in solution, comprising cellular components liberated from the plant tissue;
- removing debris from the homogenized plant tissue, if present;
- and
- optionally, dialyzing the homogenized plant tissue to remove non-complexed compounds, or removing the non-complexed compounds by size exclusion,
- thereby providing a solution comprising the nanoparticles which are formed by self-assembly of the cellular components.
A food powder comprising self-assembled cellular components derived from a homogenized plant tissue derived from cherry or sour cherry, the cellular components comprising one or more structural carbohydrates or cleavage products of one or more structural carbohydrates, and further comprising at least one nutritional agent, wherein lipids are not a structural component of the food powder.
A food powder produced by a method comprising:
- preparing a homogenized plant tissue in solution, comprising cellular components liberated from the plant tissue, the cellular components comprising one or more structural carbohydrates or cleavage products thereof, and the homogenized plant tissue in solution further comprising at least one nutritional agent;
- optionally, removing debris from the homogenized plant tissue in solution, if present;
- and
- freeze-drying, lyophilizing, spray-drying, or nanospray drying the homogenized plant tissue in solution to form the food powder.
Dependencies are inferred from the claim text.