Geometrically complex intravaginal rings, systems and methods of making the same
AssigneeThe University of North Carolina at Chapel Hill
InventorsSoumya Rahima Benhabbour, Rima Janusziewicz, Sue J. Mecham
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AssigneeThe University of North Carolina at Chapel Hill
InventorsSoumya Rahima Benhabbour, Rima Janusziewicz, Sue J. Mecham
Estimating the term…
Geometrically complex intravaginal rings, systems and methods of making the same are provided herein. Disclosed herein are geometrically complex intravaginal rings with tunable and enhanced drug release, which in some embodiments can be fabricated by 3D printing technologies. The disclosed IVRs include a ring structure comprising a plurality of unit cells or macroscopic and/or microscopic architecture, which can be tuned to control the loading capacity of an active compound within the IVR, the diffusion of an active compound from the IVR, the surface area of the IVR, and/or the mechanical properties of the IVR. The disclosed geometrically complex IVRs can provide superior control over drug loading and drug release compared to conventional IVRs fabricated by injection molding or hot-melt extrusion.
A method of fabricating a 3D printed intravaginal ring (IVR), comprising:
Dependencies are inferred from the claim text.