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US 12,404,431 B2Granted
Adhesive hydrogels and uses thereof
AssigneeThe Trustees of the University of Pennsylvania
InventorsDaeyeon Lee, Kathleen J. Stebe, Laura Bradley
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Abstract
Adhesive hydrogels comprising a (co)polymer matrix, wherein the adhesive hydrogel comprises at least one rough surface as well as processes for preparing such hydrogels are disclosed.
Claims12
An adhesive hydrogel comprising a (co) polymer matrix, wherein the adhesive hydrogel comprises at least one rough surface that includes at least one feature having a height of from about 50 micrometers to about 200 micrometers measured perpendicular to a plane in which the adhesive hydrogel lies,
- the rough surface having a topography characterized as being a peak-valley topography,
- the (co) polymer matrix comprising any one or more of (i) a homopolymer or a copolymer of 2-hydroxyethyl methacrylate, (ii) a homopolymer of poly(ethylene glycol) diacrylate or of poly(ethylene oxide), (iii) a copolymer of poly(ethylene glycol) diacrylate or of poly(ethylene oxide), (iv) a homopolymer or a copolymer of poly(propylene oxide), (v) a homopolymer of a copolymer of poly(acrylic acid), (vi) a homopolymer or a copolymer of poly(vinyl alcohol), or (vii) a polysaccharide-based (co) polymer,
- wherein the topography of the rough surface is randomly arranged, and
- wherein valleys of the peak/valley topography form a randomly-arranged network of microchannels that allow fluids to drain from contact points between a substrate when contacted to the adhesive hydrogel.
1 more element
Dependencies are inferred from the claim text.