Glycolipopeptide biosurfactants
AssigneeCroda International PLC
InventorsRussell Greig Kerr, Bradley Arnold Haltli, Douglas Hubert Marchbank, Fabrice Berrué
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AssigneeCroda International PLC
InventorsRussell Greig Kerr, Bradley Arnold Haltli, Douglas Hubert Marchbank, Fabrice Berrué
Estimating the term…
Surfactants based on a newly discovered class of compounds include a hydrophobic lipid oligomer covalently linked to a peptide or peptide-like chain and a carbohydrate moiety, and a serine-leucinol dipeptide linked to the lipid oligomer. Such surfactants can be used to create an oil-in-water or water-in-oil emulsion by mixing together a polar component; a non-polar component; and the surfactant. Biosurfactants of the newly discovered class can be made by isolating and culturing a microorganism which produces the biosurfactant, and then isolating the biosurfactant from the culture. A microorganism can be engineered to produce biosurfactant of this newly discovered class by expressing a set of heterologous genes involved in the biosynthesis of the biosurfactant in the microorganism.
A purified biosurfactant comprising a hydrophobic lipid component comprising a carboxyl end and a hydroxyl end, wherein the lipid component is covalently linked to (i) a peptide or nonproteinogenic amino acid chain at the carboxyl end of the lipid component and (ii) a carbohydrate moiety at the hydroxyl end of the lipid component via a glycosidic linkage, wherein the carbohydrate moiety includes one, two or three rhamnose moieties, wherein one or more rhamnose hydroxy groups are acetylated if there is one rhamnose moiety and two or more rhamnose hydroxy groups are acetylated if there are two rhamnose moieties.
Dependencies are inferred from the claim text.