Release of growth factors at wound healing stages
AssigneesBoard of Trustees of the University of Arkansas, National University Corporation Okayama University
InventorsJoshua Sakon, Robert Beitle, Hazim Aljewari, Osamu Matsushita, Stephanie Beitle
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Abstract
The present invention provides collagen-binding agents that can be used to treat wounds, ischemic heart disease, and other conditions. The collagen-binding agents comprise a therapeutic agent, a protease cleavage site, and a collagen-binding domain. The present invention further provides pharmaceutical compositions and biomedical devices comprising the disclosed collagen-binding agents, as well as methods for treating a condition using the collagen-binding agents.
Claims6
A collagen-binding agent comprising SEQ ID NO:1.
Dependencies are inferred from the claim text.