Hyperspectral/multispectral imaging system with simultaneous white light imaging

A method comprising:

• causing a light source for a medical scope to provide white light illumination for frames at a first frame rate suitable for live video;
• causing the light source to interrupt the white light illumination and provide narrowband illumination for individual frames interspersed among the white light illuminated frames at regular or irregular intervals, wherein the narrowband spectrum varies amongst the interspersed frames sufficient for a series of at least two differently illuminated narrowband interspersed frames to be assembled into a multispectral or hyperspectral data cube at a second frame rate;
• imaging the white light illuminated fames and narrowband illuminated frames onto a focal plane array image sensor at the medical scope;
• at a processor, receiving an image signal based on sensor data received from the focal plane array sensor and creating a live video feed based on the white light illuminated frames by replacing the narrowband illuminated frames with frames generated from one or more time-adjacent white light illuminated frames;
• and
• at the processor, generating a multispectral or hyperspectral data cube at a second frame rate based on the narrowband illuminated frames.