Therapeutic oligonucleotides
AssigneeCaris Science, Inc.
InventorsHeather O'Neill, Günter Mayer, Mark Miglarese, David Spetzler
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Abstract
Methods and compositions are provided for oligonucleotides that bind targets of interest. The targets include cells and microvesicles, such as those derived from various diseases. The oligonucleotides can be used for diagnostic and therapeutic purposes. The target of the oligonucleotides can be a target such as PARP1, HIST1H1B, HIST1H1D, NCL, FBL, SFPQ, RPL12, ACTB, HIST1H4A, SSBP1, NONO, H2AFJ, and DDX21, or a complex, subunit or fragment thereof.
Claims14
An oligonucleotide attached to a cytotoxic moiety or a therapeutic agent or a diagnostic agent, wherein the oligonucleotide comprises a sequence according to SEQ ID NO:
- 4357.
Dependencies are inferred from the claim text.