Nucleoside derivative and use thereof

Abstract

Provided is a nucleoside derivative represented by the following formula (1): or a salt thereof, wherein R1 represents an alkoxy group, a hydrogen atom or a halogen atom; R2 and R4, which may be the same as or different from each other, each represents a hydrogen atom, a protective group for a hydroxyl group, a phosphate group, a protected phosphate group, or —P(═O)nR5R6 in which n represents 0 or 1, R5 and R6, which may be the same as or different from each other, each represents a hydrogen atom, a hydroxyl group, a protected hydroxyl group, a mercapto group, a protected mercapto group, an alkoxy group, a cyanoalkoxy group, an amino group, or a substituted amino group, provided that when n is 1, both R5 and R6 cannot be the hydrogen atom at the same time; R3 represents —(CH2)mNHR7 in which m represents an integer of 1 to 6, R7 represents a hydrogen atom, an alkyl group, an alkenyl group or a protective group for an amino group; and B represents a purin-9-yl group, a 2-oxo-pyrimidin-1-yl group, a substituted purin-9-yl group, or a substituted 2-oxo-pyrimidin-1-yl group.

Dependencies are inferred from the claim text.