2-amino-2-(1,2,3-triazole-4-yl)propane-1,3-diol derivative of novel compound for directly inhibiting ASM activity, and use thereof
AssigneeKyungpook National University Industry-Academic Cooperation Foundation
InventorsJae-Sung Bae, Hee Kyung Jin, Min Hee Park
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Abstract
The present invention relates to a composition for preventing or treating neurodegenerative diseases or depression, containing a 2-amino-2-(1,2,3-triazole-4-yl)propane-1,3-diol derivative as an active ingredient and more specifically, to a pharmaceutical composition for preventing or treating neurodegenerative diseases or depression, containing, as an active ingredient, the compound having an effect of directly inhibiting ASM activity.
Claims10
A compound of Chemical Formula 1 below or a salt thereof:
- wherein, R1 is hydrogen, and R2 is alkyl of 6 to 9 carbon atoms.
A composition comprising a compound of Chemical Formula 1 below or a pharmaceutically acceptable salt thereof:
- wherein, R1 is hydrogen, and R2 is alkyl of 6 to 9 carbon atoms.
A composition comprising a compound of Chemical Formula 1 below or a pharmaceutically acceptable salt thereof and a diagnostic agent or detection agent:
- wherein R1 is hydrogen, and R2 is alkyl of 6 to 9 carbon atoms.
A method for treating a neurodegenerative disease or depression comprising administering an effective amount of a composition containing a compound of Chemical Formula 1 below or a pharmaceutically acceptable salt thereof to a subject in need thereof:
- wherein, R1 is hydrogen and R2 is alkyl of 6 to 9 carbon atoms.
A method for diagnosing a neurodegenerative disease or depression comprising administering an effective amount of a composition containing a compound of Chemical Formula 1 below or a pharmaceutically acceptable salt thereof to which a diagnostic agent or detection agent is bound to a subject suspected of a neurodegenerative diseases or depression:
- wherein, R1 is hydrogen, and R2 is alkyl of 6 to 9 carbon atoms.
Dependencies are inferred from the claim text.