Patterned, dendrimeric substrate surfaces and production and use thereof
AssigneeKarlsruher Institut für Technologie
InventorsMaximilian Benz, Pavel A. Levkin
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Abstract
The present invention relates to a patterned substrate comprising first regions having first dendrimer structures and second regions having second dendrimer structures on a surface of the substrate, as well as a to method for manufacturing a patterned substrate and the use of a patterned substrate for the chemical synthesis of a chemical synthesis product, as a characterizing platform and/or as a platform for cell treatment and/or cell cultivation.
Claims20
A patterned substrate comprising first regions and second regions on a surface of the substrate, wherein
- the first regions have first dendrimer structures and the second regions have second dendrimer structures;
- the dendrimer structures are each covalently connected with the substrate surface;
- the second regions enclose the first regions;
- and
- the second dendrimer structures have at least one structural element different from the structural elements of the first dendrimer structures;
- wherein the first dendrimer structures have terminal groups having the following general formula (4) or (5)
- wherein X and Z are independently from each other NR3 or O, wherein each R3 is independently from each other selected from the group consisting of hydrogen, an alkyl group, a cycloalkyl group, an aryl group, and a heteroaryl group;
- wherein R4 is selected from the group consisting of -NG1G2, —NO2, —CN, -OG3, —C(O)G4, C(O)NG5G6, -COOG7 and —SO3G8, wherein G1 to G8 are independently from each other selected from the group consisting of hydrogen, an alkyl group, a cycloalkyl group, an aryl group, and a heteroaryl group;
- and
- o is an integer from 1 to 6.
A patterned substrate comprising first regions and second regions on a surface of the substrate, wherein
- the first regions have first dendrimer structures and the second regions have second dendrimer structures;
- the dendrimer structures are each covalently connected with the substrate surface;
- the second regions enclose the first regions;
- and
- the second dendrimer structures have at least one structural element different from the structural elements of the first dendrimer structures;
- wherein the second dendrimer structures have terminal groups having the following general formula (6)
- wherein p is an integer from 0 to 10 and
- q is an integer from 3 to 15.
Dependencies are inferred from the claim text.