Back to results
US 12,397,156 B2Granted
Devices, systems, and methods for incontinence control
AssigneeAmber Therapeutics Holdings Limited
InventorsTimothy Denison, Stefan De Wachter, Charles Knowles, Aidan Crawley
Life of this patent
Estimating the term…
Abstract
Provided are devices and methods for preventing an episode of incontinence in an individual in need thereof. The devices comprise a sensor and a stimulator electrode that can be implanted into the body of the individual. Once the device is implanted in the individual, the sensor of the device senses a parameter that is associated with a response from the individual that is intended to prevent an episode of incontinence. Then, the device provides an electrical stimulation using the electrode that, together with the response, helps to prevent the episode of incontinence.
Claims90
A system for preventing an episode of incontinence of a patient, the system comprising:
- a first lead and a second lead configured to be implanted bilaterally proximate a pudendal nerve;
- a first sensor electrode and a second sensor electrode configured to detect a parameter indicative of the patient's effort to prevent an episode of incontinence;
- a first stimulator electrode and a second stimulator electrode configured to provide an electrical stimulation at or near the pudendal nerve;
- wherein the first lead comprises the first sensor electrode and the first stimulator electrode;
- wherein the second lead comprises the second sensor electrode and the second stimulator electrode;
- and
- an implantable pulse generator operably coupled to the first and second stimulator electrodes and the first and second sensor electrodes;
- wherein the implantable pulse generator is configured to provide a base stimulation level;
- wherein in response to detecting the parameter indicative of the patient's effort to prevent the episode of incontinence, the implantable pulse generator is configured to provide an activated electrical stimulation level configured to prevent the episode of incontinence;
- wherein the activated electrical stimulation level is higher than the base stimulation level;
- and
- wherein the implantable pulse generator is further configured to provide the activated electrical stimulation level to the same lead that detected the parameter indicative of the patient's effort to prevent the episode of incontinence.
9 more elements
A system for ameliorating an episode of incontinence of a patient, the system comprising:
- a first sensor electrode configured to detect an EMG signal indicative of the patient's effort to ameliorate an episode of incontinence;
- a second sensor configured to sense a second parameter indicative of the patient's effort to prevent the episode of incontinence;
- at least one stimulator electrode configured to provide an electrical stimulation at or near a pudendal nerve;
- and
- an implantable pulse generator operably coupled to the at least one stimulator electrode and the first sensor electrode;
- wherein the implantable pulse generator is configured to provide a base stimulation level;
- wherein in response to detecting the EMG signal indicative of the patient's effort to prevent the episode of incontinence and the second parameter, the implantable pulse generator is configured to provide an activated electrical stimulation level configured to ameliorate the episode of incontinence;
- wherein the activated electrical stimulation level is higher than the base stimulation level.
5 more elements
A system for ameliorating an episode of incontinence of a patient, the system comprising:
- a first sensor electrode configured to detect an EMG signal indicative of the patient's effort to ameliorate an episode of incontinence;
- at least one stimulator electrode configured to provide an electrical stimulation at or near a pudendal nerve;
- and
- an implantable pulse generator operably coupled to the at least one stimulator electrode and the first sensor electrode;
- wherein the implantable pulse generator is configured to provide a base stimulation level, wherein the base stimulation level has a constant frequency;
- wherein in response to detecting the EMG signal indicative of the patient's effort to prevent the episode of incontinence, the implantable pulse generator is configured to provide an activated electrical stimulation level configured to ameliorate the episode of incontinence;
- wherein the activated electrical stimulation level is higher than the base stimulation level.
4 more elements
A system for ameliorating an episode of incontinence of a patient, the system comprising:
- a first sensor electrode configured to detect an EMG signal indicative of the patient's effort to ameliorate an episode of incontinence;
- at least one stimulator electrode configured to provide an electrical stimulation at or near a pudendal nerve;
- and
- an implantable pulse generator operably coupled to the at least one stimulator electrode and the first sensor electrode;
- wherein the implantable pulse generator is configured to provide a base stimulation level, wherein the base stimulation level has a constant amplitude;
- wherein in response to detecting the EMG signal indicative of the patient's effort to prevent the episode of incontinence, the implantable pulse generator is configured to provide an activated electrical stimulation level configured to ameliorate the episode of incontinence;
- wherein the activated electrical stimulation level is higher than the base stimulation level.
4 more elements
A system for ameliorating an episode of incontinence of a patient, the system comprising:
- a first sensor electrode configured to detect an EMG signal indicative of the patient's effort to ameliorate an episode of incontinence;
- at least one stimulator electrode configured to provide an electrical stimulation at or near a pudendal nerve;
- and
- an implantable pulse generator operably coupled to the at least one stimulator electrode and the first sensor electrode;
- wherein the implantable pulse generator is configured to provide a base stimulation level, wherein the base stimulation level has a constant current;
- wherein in response to detecting the EMG signal indicative of the patient's effort to prevent the episode of incontinence, the implantable pulse generator is configured to provide an activated electrical stimulation level configured to ameliorate the episode of incontinence;
- wherein the activated electrical stimulation level is higher than the base stimulation level.
4 more elements
A system for ameliorating an episode of incontinence of a patient, the system comprising:
- a first sensor electrode configured to detect an EMG signal indicative of the patient's effort to ameliorate an episode of incontinence;
- at least one stimulator electrode configured to provide an electrical stimulation at or near a pudendal nerve;
- and
- an implantable pulse generator operably coupled to the at least one stimulator electrode and the first sensor electrode;
- wherein the implantable pulse generator is configured to provide a base stimulation level;
- wherein in response to detecting the EMG signal indicative of the patient's effort to prevent the episode of incontinence, the implantable pulse generator is configured to provide an activated electrical stimulation level configured to ameliorate the episode of incontinence and the activated electrical stimulation level changes a pulse width of electrical stimulation;
- wherein the activated electrical stimulation level is higher than the base stimulation level.
4 more elements
A system for ameliorating an episode of incontinence of a patient, the system comprising:
- a first sensor electrode configured to detect an EMG signal indicative of the patient's effort to ameliorate an episode of incontinence;
- at least one stimulator electrode configured to provide an electrical stimulation at or near a pudendal nerve;
- and
- an implantable pulse generator operably coupled to the at least one stimulator electrode and the first sensor electrode;
- wherein the implantable pulse generator is configured to provide a base stimulation level;
- wherein in response to detecting the EMG signal indicative of the patient's effort to prevent the episode of incontinence, the implantable pulse generator is configured to provide an activated electrical stimulation level configured to ameliorate the episode of incontinence and the activated electrical stimulation level changes a frequency of electrical stimulation;
- wherein the activated electrical stimulation level is higher than the base stimulation level.
4 more elements
A system for ameliorating an episode of incontinence of a patient, the system comprising:
- a first sensor electrode configured to detect an EMG signal indicative of the patient's effort to ameliorate an episode of incontinence;
- at least one stimulator electrode configured to provide an electrical stimulation at or near a pudendal nerve;
- and
- an implantable pulse generator operably coupled to the at least one stimulator electrode and the first sensor electrode;
- wherein the implantable pulse generator is configured to provide a base stimulation level;
- wherein in response to detecting the EMG signal indicative of the patient's effort to prevent the episode of incontinence, the implantable pulse generator is configured to provide an activated electrical stimulation level configured to ameliorate the episode of incontinence and the activated electrical stimulation level changes an amplitude of electrical stimulation;
- wherein the activated electrical stimulation level is higher than the base stimulation level.
4 more elements
A system for ameliorating an episode of incontinence of a patient, the system comprising:
- a first sensor electrode configured to detect an EMG signal indicative of the patient's effort to ameliorate an episode of incontinence;
- a second sensor configured to sense a second parameter indicative of the patient's effort to prevent the episode of incontinence, the second sensor configured to sense physical movement of the patient;
- at least one stimulator electrode configured to provide an electrical stimulation at or near a pudendal nerve;
- and
- an implantable pulse generator operably coupled to the at least one stimulator electrode and the first sensor electrode;
- wherein the implantable pulse generator is configured to provide a base stimulation level;
- wherein in response to detecting the EMG signal indicative of the patient's effort to prevent the episode of incontinence and the second parameter, the implantable pulse generator is configured to provide an activated electrical stimulation level configured to ameliorate the episode of incontinence;
- wherein the activated electrical stimulation level is higher than the base stimulation level.
5 more elements
A system for ameliorating an episode of incontinence of a patient, the system comprising:
- a first sensor electrode configured to detect an EMG signal indicative of the patient's effort to ameliorate an episode of incontinence;
- a second sensor configured to sense a second parameter indicative of the patient's effort to prevent the episode of incontinence, wherein the second sensor comprises an accelerometer;
- at least one stimulator electrode configured to provide an electrical stimulation at or near a pudendal nerve;
- and
- an implantable pulse generator operably coupled to the at least one stimulator electrode and the first sensor electrode;
- wherein the implantable pulse generator is configured to provide a base stimulation level;
- wherein in response to detecting the EMG signal indicative of the patient's effort to prevent the episode of incontinence and the second parameter, the implantable pulse generator is configured to provide an activated electrical stimulation level configured to ameliorate the episode of incontinence;
- wherein the activated electrical stimulation level is higher than the base stimulation level.
5 more elements
A system for ameliorating an episode of incontinence of a patient, the system comprising:
- a first sensor electrode configured to detect an EMG signal indicative of the patient's effort to ameliorate an episode of incontinence;
- a second sensor configured to sense a second parameter indicative of the patient's effort to prevent the episode of incontinence, wherein the second sensor comprises a pressure sensor;
- at least one stimulator electrode configured to provide an electrical stimulation at or near a pudendal nerve;
- and
- an implantable pulse generator operably coupled to the at least one stimulator electrode and the first sensor electrode;
- wherein the implantable pulse generator is configured to provide a base stimulation level;
- wherein in response to detecting the EMG signal indicative of the patient's effort to prevent the episode of incontinence and the second parameter, the implantable pulse generator is configured to provide an activated electrical stimulation level configured to ameliorate the episode of incontinence;
- wherein the activated electrical stimulation level is higher than the base stimulation level.
5 more elements
Dependencies are inferred from the claim text.