Anti-microbial blue light systems and methods

A system for providing treatment to tissue, comprising:

• a light source configured to provide light energy at a plurality of frequencies;
• a delivery catheter having an elongated shaft and an inner lumen therethrough;
• and
• one or more optical fibers sized to pass through the inner lumen of the delivery catheter and being configured to deliver the light energy from the light source to provide an antimicrobial effect to the tissue, the one or more optical fibers being configured to disperse the light energy such that intensity of the light energy is distributed evenly over a length of the one or more optical fibers in both longitudinal and circumferential directions;
• wherein the one or more optical fibers include a cladding covering an outer surface thereof, and wherein at least a portion of the cladding of the one or more optical fibers is removed from an outer surface of the one or more optical fibers to achieve the even dispersion of the light energy,
• wherein the at least a portion of the cladding is removed to form a helical spiral along the length of the one or more optical fibers, wherein a depth of the removal of the cladding increases as the helical spiral moves from a proximal end of the one or more optical fibers to a distal end of the one or more optical fibers to achieve an even light distribution over the length of the one or more optical fibers, and
• wherein the antimicrobial effect of the light energy is configured to reduce an amount of one or more pathogens in a bone.

A system for providing treatment to tissue, comprising:

• a light source configured to provide light energy having a selected power associated therewith;
• a delivery catheter having an elongated shaft and an inner lumen therethrough;
• and
• one or more optical fibers configured to include a cladding covering an outer surface thereof and sized to pass through the inner lumen of the delivery catheter and being configured to deliver the light energy from the light source to provide an antimicrobial effect to the tissue, the one or more optical fibers being configured to disperse the light energy such that intensity of the light energy is distributed evenly over a length of the one or more optical fibers with an even power distribution over the length of the one or more optical fibers based on the selected power,
• wherein a portion of the cladding is removed in a helical spiral that is configured to become increasingly tight as the helical spiral moves from a proximal end of the one or more optical fibers to a distal end of the one or more optical fibers to achieve an even light distribution over the length of the one or more optical fibers.

A system for providing treatment to tissue, comprising:

• a delivery catheter having an elongated shaft and an inner lumen therethrough;
• and
• one or more optical fibers sized to pass through the inner lumen of the delivery catheter and being configured to deliver light energy to provide an antimicrobial effect to the tissue, the one or more optical fibers being configured to disperse the light energy such that intensity of the light energy is distributed evenly over a length of the one or more optical fibers in both longitudinal and circumferential directions;
• wherein the one or more optical fibers include a cladding covering an outer surface thereof, and wherein at least a portion of the cladding of the one or more optical fibers is removed from an outer surface of the one or more optical fibers to form a helical spiral along the length of the one or more optical fibers, wherein a depth of the removal of the cladding increases as the helical spiral moves from a proximal end of the one or more optical fibers to a distal end of the one or more optical fibers to achieve the even dispersion of the light energy,
• wherein the antimicrobial effect of the light energy is configured to kill bacteria to treat bone infections.