Clostridioides difficile

A method of treating, preventing or ameliorating a Clostridioides difficile infection by selectively inhibiting the growth of Clostridioides difficile, the method comprising administering, to a subject in need thereof, a therapeutically effective amount of a compound of Formula (I):

• wherein R1 is a C4 to C6 alkyl or fluorinated alkyl;
• and
• R2 is hydrogen or a C1 to C4 alkyl or halogenated alkyl, and the C1 to C4 alkyl or halogenated alkyl is optionally substituted with between 1 and 5 substituents, wherein each substituent has the formula:
• wherein each R3 is independently a C2 to C10 alkyl or halogenated alkyl;
• or a pharmaceutically acceptable salt of the compound of Formula I, solvate of the compound of Formula I, tautomeric form of the compound of Formula I or polymorphic form of the compound of Formula I.