Reinforced gas-permeable membrane and reinforced gas-permeable well utilizing same
AssigneeBroadley-James Corporation
InventorsChang-Dong Feng, Josh L. Rothman, Robert J. Garrahy, Scott T. Broadley
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Abstract
A gas-permeable well for use with a bioreactor may include a reinforced gas-permeable membrane. The gas-permeable membrane may include an integrated reinforcing structure such as a stainless steel mesh or perforated screen, and may include an integrated gasket or O-ring, or other regions of increased thickness. A sensor brought into close proximity to the reinforced gas-permeable membrane may take an indirect measurement of a condition of process medium on the other side of the gas-permeable membrane, such as a measurement of dissolved oxygen or carbon dioxide.
Claims22
A reinforced gas-permeable well for use with a bioreactor, the reinforced gas-permeable well comprising:
- a reinforced gas-permeable membrane, the reinforced gas-permeable membrane comprising:
- a gas-permeable membrane;
- and
- a gas-impermeable reinforcing structure at least partially embedded within the gas-permeable membrane, the gas-impermeable reinforcing structure including at least one aperture extending therethrough;
- and
- a retaining structure configured to retain the gas-permeable membrane.
A reinforced gas-permeable well for use with a bioreactor, the reinforced gas-permeable well comprising:
- a reinforced gas-permeable membrane, the reinforced gas-permeable membrane including a reinforcing structure which decreases the permeability of the gas-permeable membrane in an area adjacent the reinforcing structure;
- and
- a retaining structure configured to retain the reinforced gas-permeable membrane.
Dependencies are inferred from the claim text.